M1216 Significant Numbers of Celiac Patients On a Gluten-Free Diet Do Not Meet RNI Targets for Micronutrients

layer. One patient showed strong IgA and IgG staining of enterocyte-cytoplasm and -brushborder, respectively, characteristic for AIE. A second patient showed only moderate IgA staining of enterocytes. Furthermore, the third patient showed strong IgG staining of the extracellular martix of enterocytes. The latter “chicken-wire” staining pattern is characteristic for auto-immune pemphigus. Conclusions: Our results indicate that some cases of persisting villous atrophy are not associated with RCD. These cases should be considered candidates for AIE or other intestinal auto-immune phenomena, including a pemphigus-like intestinal disorder. Correct identification of such patients is pivotal, in view of different treatment regimens. We propose routine screening for the presence of enterocyte auto-antibodies is included in the diagnostic work-up for RCD.