Wady zastawkowe serca i różne profile dobowe ciśnienia tętniczego.

Valvular heart diseases (VHD) increase the risk of cardiovascular morbidity and mortality. Little is known about correlation between circadian blood pressure profile and VHD. The aim of the study was to clarify the association of dipping status and VHD prevalence. 103 consecutive patients (male: 50.5%), who underwent 24-hour ambulatory BP measurement and ECG-Holter simultaneously were analysed. We divided patients into 3 groups: dipping was defined as 10-20% (28.2%), non-dipping as < 10% (50.5%) fall in nocturnal BP and reverse-dipping as higher nocturnal than diurnal BP (21.4%). VHD was assessed by transthoracic echocardiography and described as mild, moderate or severe regurgitation or stenosis accordingly. Further we compared severity of VHD, nocturnal fall pattern and ABPM features in all groups. We found no statistically significant associations between dipping pattern and frequency of VHD. We also found no statistical association between dipping status and severity of VHD. Our study showed some correlations between VHD severity and different ABPM parameters. Though dipping status obtained by ABPM did not influence severity of VHD, there were associations between ABPM outcomes and VHD. This finding may have important implications on care of patients with hypertension and VHD, though further studies are needed.