Tratamiento de la encefalopatía mioclónica de la infancia (síndrome de Kinsbourne) con metotrexate y gammaglobulina endovenosa

Myoclonic encephalopathy of infancy is an important model of natural tumor regression. Patients with opsoclonus-myoclonus generate an immune response against a variety of brain antigens. It is probable that neuroblastoma (or viral antigens) and the cerebelum are joint targets of an immunologic attack. Most cases show a remarkable reponse to ACTH, intravenous gammaglobulin and rituximab.