Diabetic neuropathy in animal models

Diabeticneuropathyisnotasinglebutseveraldifferentpathogenic mechanisms leading to several symptoms.Diabetic animal models have been extensively used tocharacterize these mechanisms to evaluate potentialtreatments in humans. We reviewed the chronology ofthepathogenicprocessunderlyingdiabeticneuropathyoccurring in several in vivo diabetic animal models ineither type 1 or type 2.Section Editors:Cord Dohrmann, Matthias Austen, Ursula Kreuzberg –DeveloGen AG, Marie-Curie-Strasse 7, 37079 Goettingen,GermanyIntroduction