Clinical Study for the Treatment Using Clear up Heat,Resolve Phlegm and Promoting Blood Circulation in Unstable Angina Pectoris

Objective:Study the relationship between the unstable angina pectoris and inflammation,the short term clinical effect of the treatment using clear up heat,resolve phlegm and promoting blood circulation in Unstable Angina Pectoris patients,and the affect to the inflammation indices.Methods:Using 120 patients which clinical diagnosis are unstable angina pectoris,randomize to two groups,the comparison group and the therapy group.The regular treatment of the unstable angina pectoris were used in both two groups,in addition,the therapy group using the propylgallate for injection,and the modified decoction of the combination with XiaoXianXiong decocion and No.2 coronary disease prescription,and then observed the clinical treatment effect and the blood indices such as CRP,IL-6,TNF-α,and compared the change after the treatment.Results:In the therapy group,all the indices are better than the comparison group,such as the overall treatment effect including the angina,electrocardiogram,the incidence rate of the cardiovascular events,the TCM syndromes calculated points,and the comparison of the calculated points difference before and after the therapy.And the difference is significant(P0.05).About the inflammation indices,there are decrease of the CRP,IL-6,TNF-α in both groups,but more obviously in the therapy group,and the difference is significant(P0.05).Conclusion:The inflammation mechanism is important in the unstable angina pectoris;the effect of the treatment using clear up heat,resolve phlegm and promoting blood circulation in unstable angina pectoris is sure,and the inflammation reaction is decreased.The short term incidence rate of cardiovascular events is also decreased in certain degree for the unstable angina pectoris patients.