Relationship between glycemic variability and diabetic neuropathy

Glycemic variability is an independent risk factor for diabetic complications, diabetic neuropathy is the most common chronic complications of diabetes, which has been paid much attention to due to its high incidence, disability rate and mortality. In recent years, studies have confirmed that glycemic variability was closely related to diabetic neuropathy. Glycemic variability induces diabetic neuropathy mainly through a series of pathophysiological processes such as activating oxidative stress, damaging vascular endothelial function and promoting inflammatory reaction. Key words: Glycemic variability; Diabetic neuropathy; Diabetes mellitus