Risk Factors for Cardiovascular Disease in Infertile women with Polycystic Ovarian Syndrome

A study was conducted to evaluate the risk of cardiovascular disease (CVD) in infertile women with polycystic ovary disease. There were 46 test subjects in the age group of 20 to 40 years and 40 age matched healthy controls. Serum lipid profile, fasting blood sugar (FBS) and reproductive hormones namely Leutinizing hormone (LH), follicle stimulating hormone (FSH), Prolactin and Estradiol were estimated in this era of all the subjects after obtaining their informed consent. Cytoklinesis-block micronuclei (CBMN) was also evaluated and attempts were made to correlate the findings with the risk of CVD. Decreased HDL and elevated levels of all other biochemical and endocrinological parameters were observed in the test subjects. A significantly elevated level of micronuclei (MN) in the test subject along with the above parameters and body mass index (BMI) is suggestive of increased risk of CVD in PCOS.