Utilisation diagnostique et thérapeutique d'anticorps monoclonaux humains anti-D (Rho): Bilan et perspectives

Summary Human monoclonal antibodies will be essential in medicine. They are valuable tools for biological diagnosis and therapeutics. Our model, human monoclonal antibodies directed against the Rhesus D antigen can be used for the determination of the Rhesus D phenotype and for the suppression of Rh(D) immunisation in women. These new products require [1] new procedures of preparation, [2] new regulations for the quality controls, which will be discussed in this paper.