Antalgic efficacy of tiaprofenic acid in models of acute rheumatic pain

: Twenty patients suffering from acute lumbosacral syndromes (Group A) and eight patients suffering from acute gout (Group B) were treated with parenteral tiaprofenic acid (TA). In Group A TA was administered for 7 days at the dosage of 400 mg/daily for the first four days (1 200 mg vial i.m. in the morning, 1 in the evening), from the 5th to the 7th day with 200 mg/daily (1 vial in the evening) and, in Group B, TA was administered for 6 days at the dosage of 600 mg on the first day, (with 1 vial/8 hours of TA 200 mg by parenteral route) the 2nd and 3rd day with 1 vial/12 hours and the 4th and 6th day with 1 vial/daily in the evening. TA was found to be active on all clinical parameters evaluated. The tolerability was also good: only 4 patients with acute lumbosacral syndrome suffered from local pain.