Identification of Pathogens Directly From Diabetic Foot Infections by Shotgun Metagenomic Sequencing

Background Diabetic foot infections (DFIs) constitute the most common cause for diabetes-related hospitalization and lower extremity amputations. Current diagnostic methods are slow and in some cases do not detect all potential pathogens. Metagenomics sequencing has the potential to merge rapidity and comprehensive information about causative pathogens in DFIs. The aim of this study was to evaluate the potential of metagenomics strategies for DFIs.