A study of magnitude of diabetes in chronic pancreatitis

Background: Chronic pancreatitis is a heterogeneous disease which leads to endocrine and exocrine dysfunction. Diabetes in chronic pancreatitis is important. Diabetes can develop by consequences of other diseases too. Aim: To assess the magnitude of Diabetes in Chronic Pancreatitis subjects. Materials and Methods: A cross sectional study was done among chronic pancreatitis subjects. The age group studied was between 25-60 years. The study period was 6 months. The sample size was based on case records. HbA1c levels were measured at 0th day (registration), 3rd month and 6th month. Data was collected with regard to alcohol consumption and smoking habits. Results: The study group ranged between 25 to 60 years, 60 was males and 3 females. The HbA1C levels were measured and subjects classified. A total of 53 subjects were diabetic. 8 subjects were started on OHA and 45 subjects on insulin. The HbA1C levels were measured again at the end of 3rd month. The subject’s on OHA there was not much of reduction in HbA1C levels so they were stated on insulin. At the end of 6 months there was significant decrease in HbA1C levels when compared to OHA. Conclusion: Our study suggests that diabetes is common in chronic pancreatitis. Diabetes in chronic Pancreatitis was more in smokers. This study also suggests insulin therapy is more effective than OHA in chronic pancreatitis Keywords: Chronic pancreatitis (CP), Oral hypoglycaemic agents (OHA), Insulin.