Enfermedad de Kikuchi: a propósito de un caso y revisión de la literatura

2003 
Kikuchi-Fujimoto disease, also known as hystiocytic necrotizing lymphadenitis, is an unusual entity which affects predominantely young asiatic females, although its distribution is world-wide. Cardinal symptoms are feverand adenopathy, generally cervical, although generalized and extraganglionar cases have been described. Considered a self-limiting disease, it has to be differentiated by pathologic analysis from other less-benign disorders such as lymphoma or hystiocitoma, which bear worse prognosis and may require specific treatment. Although the origin of this disease is unknown, a viral origin is postulated and the inmune system is involved. Kikuchi disease has been associated to other entities such as subcutaneous lupus erythematosus, Hashimoto thyroiditis, etc...requiring patients be followed immunologically after diagnois of this disease. We present a case of Kikuchi disease associated with subacute lymphocytic thyroiditis.
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