Changes induced by carbamazepine in the action of ADH (antidiuretic hormone) in neurologic patients

: We report the result of a study performed in 27 patients taking carbamazepine because of epilepsy or neuralgia, in order to point out subclinical water abnormal retention. We tested serum sodium and potassium levels, plasma and urine osmolarity, free water clearance. The carbamazepine serum level is also reported. We didn't find abnormal values. So in our experience there is not any complication concerning water retention during oral carbamazepine treatment.