424 Could preterm delivery be a surrogate marker for accelerated development of cardiovascular events in women with sle

Background and aims Women with SLE are at greater risk of premature cardiovascular disease and adverse pregnancy outcomes including preterm delivery. In the general population, preterm delivery is associated with an increased risk of maternal cardiovascular events (CVE). Therefore, we sought to determine if preterm delivery was a surrogate marker for accelerated CVE in women with SLE. Methods Utilising linked population-based registries from Sweden between 1973–2011, women with SLE born between 1951 – 1971 were included. Preterm delivery was defined as delivery Results There were 3224 women, median age 49 years (IQR 44–54); 72% had a previous pregnancy and 6% had delivered Those with Conclusions The women with preterm deliveries