The influence of timing of polysomnography on diagnosis of obstructive sleep apnea in patients presenting with acute myocardial infarction and stable coronary artery disease

Abstract Background We aimed to determine if timing of polysomnography (PSG) influences the diagnosis of obstructive sleep apnea (OSA) in acute myocardial infarction (AMI) or stable coronary artery disease (CAD). Methods A total of 160 patients admitted with AMI or stable CAD were consecutively recruited for either in-hospital ( n =80) or postdischarge ( n =80) PSG. Results The median time from admission to PSG for the in-hospital and postdischarge groups was 1day and 17days, respectively ( P P P =.037) in patients who had a PSG performed as an inpatient than those who had a PSG as an outpatient. There was a significant interaction between clinical presentation and the effect of PSG timing on the diagnosis of OSA ( P =.003). For the patients presenting with AMI but not those with stable CAD, in-hospital PSG was an independent predictor of OSA (adjusted odds ratio, 3.84 [95% confidence interval, 1.42–10.41]; P =.008). Conclusion The timing of PSG influenced the diagnosis of OSA in patients who presented with AMI but not in those who presented with stable CAD.