Clinical and epidemiological profile of psoriasis patients: A retrospective study in tertiary medical centers, Mangalore, India
2020
Background: Psoriasis is an immune-mediated chronic skin
disorder. Information regarding its clinical and epidemiological
manifestations is limited in some parts of Asia. This study was
conducted to determine the risk factors, clinical presentation, and
management of psoriasis among patients in Mangalore, India.
Methods: The medical records of 225 psoriasis patients over the
past ten years (from January 2009 till March 2019) were examined
by the investigators. Data were collected using a semi-structured
form.
Results: The mean age at diagnosis of psoriasis was 42.2 ± 16.0
years. Nail psoriasis and psoriatic arthritis (PsA) were present
in 66 (29.3%) and 21 (9.3%) patients, respectively. Relapse of
psoriasis was seen more among patients with a history of disease
exacerbation in winter (P = 0.009) or in rainy seasons (P = 0.031).
Systemic therapy with methotrexate and topical therapy with
steroids were used in the management of 52 (23.1%) and 72
(32%) patients, respectively. Phototherapy (n = 11) was the most
common modality used among the 18 patients with extensive
psoriasis. Co-morbidities like diabetes mellitus (P = 0.02) and
complications like PsA (P = 0.008) were associated with greater
disease durations among the patients.
Conclusion: The proportion of patients with extensive psoriasis was
high in the current setting probably because of delayed diagnosis.
Awareness about the disease and its clinical manifestations might
help in its early identification. Seasonal exacerbation was an
important risk factor for psoriasis and it was associated with its
relapse. The most common management modalities were topical
steroids for psoriasis and phototherapy for extensive psoriasis.
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