Phytochemical studies and pharmacological screening of Sida rhombifolia Linn.

Plan: Anti-anxiety activity of Sida rhombifolia Linn. Prologue: Sida rhombifolia commonly called Bala or Atibala is claimed by folklore for various ailments like rheumatism, seminal weakness, and diarrhea. Earlier studies on the ethanolic extract of the roots (SRE) revealed a significant, antioxidant, antimicrobial, anti-inflammatory, hepatoprotective and antibacterial activity. The present study was designed to evaluate anti-anxiety activity of powdered whole plant extracts of Sida rhombifolia Linn. viz petroleum ether and ethanol. Methodology: Anti-anxiety activity of Sida rhombifolia Linn. were studied by using Elevated Plus Maze (EPM) model in albino mice. Outcome: Albino mice were treated orally with dose 300 mg/kg of the extract and behavior was observed on the EPM. Diazepam (2mg/kg, P.O) was used as a positive control. Result showed that alcoholic extract was found to produce very significant result. Hence, this plant may be developed as a potentially useful anti anxiety agent