In vivo production of nitric oxide in the canine heart in IgE-mediated anaphylaxis.

ABSTRACTWe investigated the production of nitric oxide (NO) in the canine anaphylactic heart in vivo using an NO-selective electrode. Seven dogs with positive sensitivity to Ascaris Suum were studied. Ascaris Suum was administered into the systemic circulation to induce anaphylaxis, and NO, blood pr