Abstract 13695: Prevalence of Mechanical Dyssynchrony in Hypertrophic Cardiomyopathy

BACKGROUND. Dyssynchrony has been extensively studied in LV systolic dysfunction, properly selecting patients for CRT. The present study has the objective to analyze the prevalence of dyssynchrony in a hypertrophic cardiomyopathy (HCM) population and its correlation with left ventricular mass related measurements and diastolic function parameters by echocardiography. METHODS/RESULTS. We included 160 patients, being 120 HCM patients and 40 controls. HCM patients had higher LV mass (286.6±106g vs 144±36g, p<0.001), septum thickness (2.0±0.5cm vs 0.9±0.1cm, p<0.001), and septum/posterior thickness ratio (1.8±0.4 vs 1.0±0.1, p<0.001). Resting LVOT gradient was 31±35mmHg in HCM patients. Derived from Doppler method, time delay (Δt) between 2 opposing walls and standard deviation of time to peak (SD) were taken from all 3 apical plane views (A4C, A2C and A3C) on basal and mid wall regions for systolic velocities (Sm) and systolic strain rate (sSR). Differences were found between all indexes originated from A4C ...