SEP-5: SUSTAINED REDUCTION OF 90-DAY MORTALITY OF SEVERE SEPSIS AND SEPTIC SHOCK AS A RESULT OF A CONTINUOUS TRAINING PROGRAM FOR PHYSICIANS AND NURSING STAFF.

Abstract Hospital mortality of severe sepsis and septic shock is about 55% in Germany. An improved compliance with the resuscitation bundle of the Surviving Sepsis Campaign significantly reduced hospital mortality. However, the long-term effect upon 90-day mortality remains unclear. In this prospective, longitudinal interventional study over 7.5 years all patients aged > 18 years with severe sepsis and septic shock treated in intensive care units (ICU) of the University Hospital of Greifswald were included. From 01/2006-12/2007, ICU-, hospital-, 28-day and 90-day mortality were registered and compared with those after the implementation of a continuous training program focusing on the resuscitation bundle (01/2008-07/2013). There was a sustained reduction of ICU-, hospital-, 28-day and 90-day mortality for anesthesiological and medical ICUs (p