Experience with ceftazidime–avibactam treatment in a tertiary care center in Saudi Arabia

Abstract Introduction Carbapenem-resistant organisms have become major healthcare-associated pathogens and are responsible for significant morbidity and mortality worldwide. Cases and managements This case-series describes our experience with ceftazidime–avibactam in the treatment of six cases with carbapenem-resistant organisms in King Abdulaziz Medical City in Riyadh, Saudi Arabia. After trying various combinations of antibiotic therapies without improvement, cases were treated with ceftazidime–avibactam. Outcomes Five of the six achieved complete cure, both clinically and microbiologically.