Concurrent Development of Hemiplegia and Angina Pectoris in a 46-year-old Man with Familial Hypercholesterolemia and Elevated Serum Lp (a) Concentrations

We report a 46-year-old man with familial hypercholesterolemia who simultaneously developed angina pectoris and left hemiplegia. Angiography revealed complete tapering occlusion of the right internal carotid artery and a 75% stenosis of the right coronary artery. In addition to hypercholesterolemia, his serum Lp(a) levels were very high, with a mean (+/- SE) of 62 +/- 2 mg/dl.