SIMPHYS: A Knowledge Base System in Syndrome Diagnostics

1984 
A disease represents a complete chain between the patterns of symptoms and the nature and causes of the disorder. Contrary to this, patterns of symptoms and a syndrome do not show such clear relationships. As the pattern appears to be very accidental, the diagnosis of a syndrome is very difficult. In addition, the number of syndromes is increasing and the physician ca find himself overtasked in keeping in mind more than perhaps 200 different patterns, each defining a syndrome.
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