Abstract 10211: Transient Ischemia Increases Transfection Efficiency of Intracoronary Ad5Luc in Pig Heart In Situ

Jakob Vinten-Johansen,L. Susan Schmarkey,Rong Jiang,Weiwei Shi,Robert L. Engler,Gabor M. Rubanyi

Abstract 10211: Transient Ischemia Increases Transfection Efficiency of Intracoronary Ad5Luc in Pig Heart In Situ

2010

Jakob Vinten-Johansen
L. Susan Schmarkey
Rong Jiang
Weiwei Shi
Robert L. Engler
Gabor M. Rubanyi

Background: Efficiency of intracoronary adenoviral vector (Ad) uptake in the heart may be impaired by permeability barrier function of the vascular endothelium. Substances that increase vascular pe...

Keywords:

Diabetes mellitus
Cardiology
Internal medicine
Transfection
Transient ischemia
Medicine
In situ
Genetic enhancement
Permeability (electromagnetism)
Viral vector
Angiogenesis
Barrier function

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