phosphorylation of CaMKII in cardiac hypertrophy from spontaneously hypertensive rats

/calmodulin-depen-dent protein kinase II (CaMKII)-dependent pathway in hypertensivecardiac hypertrophy. Normotensive Wistar-Kyoto (WKY) rats andspontaneous hypertensive rats (SHRs) were used. Whole cell mem-brane currents were recorded in isolated ventricular myocytes by thepatch-clamp method, and apamin-sensitive K current (