Tumor markers useful in the diagnostics and monitoring of endometrial and cervical cancer

: Tumor markers play an important role in the diagnosis of cancer. Cervical carcinoma and endometrial cancer are the most frequent diseases of the reproductive organs and their morbidity rates are constantly increasing. Many tumor markers may be used in the diagnosis and monitoring of endometrial and cervical carcinoma, for example CA 125, SCC-Ag, TPA, TPS, and CYFRA 21-1. New tumor markers useful in the early diagnosis and in monitoring the treatment and recurrence of the uterine cancer are still being sought. Investigations are underway on such substances as cytokines (e.g. M-CSF) and molecular markers of carcinogenesis (e.g. K-ras and p53).