An Innovative Platform to Analyze Heart Failure Biomarkers in Saliva.

: This paper explains a methodology to improve patient safety through early detecting of HF complications and analyzing HF biomarkers in saliva obtained using a biosensor developed in HEARTEN project. A pilot study was performed in two hospitals in Spain and Italy respectively. A direct correlation was identified between TNF-alpha levels in saliva and weight. The weight gain in HF patients could predict a HF decompensation, consequently TNF-alpha could be a new biomarker of these decompensations.