Abstract WP134: Calcium Release-activated Calcium Channel Inhibition Improves Neurological Outcome and Suppresses Inflammation in Female Mice Following Cerebral Ischemic Injury

Atsushi Mizuma,Rachid Kacimi,Ken Stauderman,Michael J. Dunn,Sudarshan Hebbar,Midori A. Yenari

Abstract WP134: Calcium Release-activated Calcium Channel Inhibition Improves Neurological Outcome and Suppresses Inflammation in Female Mice Following Cerebral Ischemic Injury

2019

Atsushi Mizuma
Rachid Kacimi
Ken Stauderman
Michael J. Dunn
Sudarshan Hebbar
Midori A. Yenari

Purpose: Calcium release-activated calcium (CRAC) channels activate microglia via store-operated Ca2+entry. We previously reported that the specific CRAC channel inhibitor (CM-EX-137) had neuroprot...

Keywords:

Calcium Channel Inhibition
Inflammation
Calcium
Physical therapy
Pharmacology
Diabetes mellitus
Medicine
ischemic injury

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