Diagnostic Validity of High-Density Barium Sulfate in Gastric Cancer Screening by Record Linkage with the Osaka Cancer Registry –AUC Analyses of Sensitivity and Specificity on Sex and Ages of Subjects–

High-density barium sulfate (HDB) has been recommended by the Japanese Society of Gastroenterological Cancer Screening (JSGCS) and used in many medical facilities. However, it is not confirmed that the new method using HDB is superior in diagnostic validity compared to the conventional method using moderate-density barium sulfate (MDB). Pre viously, the authors reported that both methods showed simi lar validity in terms of sensitivity and specificity in gastric cancer screening. In this study, sensitivity and specificity were re-examined in more detail by area under receiver-operating characteristic (ROC) curves (AUC) analysis, especially on the sex (male, female) and the ages (>50, 55, 60, <60) of subjects. The results showed that the diagnostic validity of the method using HDB is almost same to that of the conven tional method using MDB. Clinical improvement in gastric cancer screening is in need of further studies on the new me thod using HDB.