Investigating the Effect of Vitamin D Prescription on the Recovery Progress of Infants and Children with Congenital Heart Disease Requiring Reconstructive Heart Surgery

Introduction Regular consumption of vitamin D doses can empower heart function in patients with heart failure. We aimed to investigate the effect of vitamin D on the recovery process of neonates, infants and children with congenital heart disease (CHD) following reconstructive cardiac surgery. Method In this single-blind clinical trial study, 46 children with CHD candidate for reconstructive cardiac surgery, who had referred to the heart department of Razi Hospital affiliated to Birjand University of Medical Sciences, Iran in 2019, were selected and randomly divided to the intervention and control groups. Patients in the intervention group received orally vitamin D before operation (300,000 units of vitamin D). 24 and 48 hours after the completing the operation, the patient's symptoms (heart rate, blood pressure, urinary output, coldness of the organd, cardiac arrest, heart function status, etc.) were assessed and inotropic drugs were prescibed according to the patient's condition. Results The mean of vitamin D level was 33.21 ± 4.66 ng/ml in the experimental group (with vitamin D) and 23.55 ± 2.68 ng/ml in the control group, respectively (P<0.05). The mean score RACH category in the patients of the experimental group was 2.33 ±0.15 and in the control group is 2.2 ± 0.14; there was no significant difference between the two groups in this regard. In two groups, the relationship between vitamin D level with RACH category score, cardiac inotrope score and vasoactive inotrope score was not significant at 24 and 48 hours after operation. Conclusion Based on the results, prescription of vitamin D did not have a significant effect on the improvement of patients with congenital cardiac disease after reconstructive heart surgery.