Therapeutics course of childhood noninfectious uveitis

Purpose Childhood noninfectious uveitis is a relatively uncommon but severe disease. All cases seen at the Tours's Hospital were included in this study and were equally followed by the multidisciplinary consultation to evaluate our practice over time. Methods 44 children followed from 2003 to 2013 were included. Demographic criteria (gender, age, type of uveitis, initial and final clinical description) and therapeutic outlines were recorded. A vision quality questionnaire Eye–Q associated with a tolerance questionnaire were sent to all patients. Results 66% were girls, the average age of diagnosis is 6.5 years and 48% of cases were JIA. Average final visual acuity was approximately 20/20. The initial treatment was topical corticotherapy alone in 47% of cases, and 42% associated with oral corticosteroids. Since the introduction of our multidisciplinary consultation, the delay in determining the change in treatment has been decreased (p = 0.001) without modifying neither the duration nor the dose of corticosteroid therapy. 16% developed new ocular complication during average follow-up of 39 months. 60% of the ocular complications de novo could be topical corticosteroid related. The response rate was 62% and 66% with preserved quality of vision. The Eye – Q score was correlated with the visual acuity but not with the duration or the doses of any treatments. Conclusions Our population showed similarity to that of the literature, except for the early support. Our Visual and inflammatory results were satisfactory, which could be explained by the introduction of our multidisciplinary consultation allowing a faster adaptability of therapeutics.