Lessons from a Minimal Genome: What Are the Essential Organizing Principles of a Cell Built from Scratch?
2019
: One of the primary challenges facing synthetic biology is reconstituting a living system from its component parts. A particularly difficult landmark is reconstituting a self-organizing system that can undergo autonomous chromosome compaction, segregation, and cell division. Here, we discuss how the syn3.0 minimal genome can inform us of the core self-organizing principles of a living cell and how these self-organizing processes can be built from the bottom up. The review underscores the importance of fundamental biology in rebuilding life from its molecular constituents.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
98
References
2
Citations
NaN
KQI