IMPACT OF TREATMENT CROSSOVERS ON CLINICAL OUTCOMES IN THE RATE AND RHYTHM CONTROL STRATEGIES FOR ATRIAL FIBRILLATION: INSIGHTSFROM THE AFFIRM (ATRIAL FIBRILLATION FOLLOW-UP INVESTIGATION OF RHYTHM MANAGEMENT) TRIAL

Background: Limited data exist on the outcomes of patients who cross over to alternative strategies of rate and rhythm control for atrial fibrillation (AF). We investigated the reasons for crossover to alternative treatment strategies and its impact on mortality in patients who were enrolled in the