One-Year Feasibility Study of Replenish MicroPump for Intravitreal Drug Delivery: A Pilot Study

Juan-Carlos Gutiérrez-Hernández,Sean Caffey,Walid Abdallah,Phillip Calvillo,Roberto Gonzalez,Jason Shih,Jeff Brennan,Jenna Zimmerman,Juan-Carlos Martínez-Camarillo,Anthony R. Rodriguez,Rohit Varma,Arturo Santos,Gisela Sánchez,Mark S. Humayun

One-Year Feasibility Study of Replenish MicroPump for Intravitreal Drug Delivery: A Pilot Study

2014

Juan-Carlos Gutiérrez-Hernández
Sean Caffey
Walid Abdallah
Phillip Calvillo
Roberto Gonzalez
Jason Shih
Jeff Brennan
Jenna Zimmerman
Juan-Carlos Martínez-Camarillo
Anthony R. Rodriguez
Rohit Varma
Arturo Santos
Gisela Sánchez
Mark S. Humayun

Purpose To determine the feasibility of the surgical procedure and to collect some safety data regarding the bioelectronics of a novel micro drug pump for intravitreal drug delivery in a Beagle dog model for up to 1 year.

Keywords:

Drug delivery
Drug
Bioelectronics
Micropump
Implantation procedure
Surgery
Medicine
Pars plana
Histopathology
Catheter
tissue ingrowth
Animal model
Beagle

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