Gastric emptying in healthy newborns fed an intact protein formula, a partially and an extensively hydrolysed formula.

Summary Background & aims: Gastric emptying (GE) is influenced by the type of nutrition. The objective of this study was to compare GE in infants fed an intact protein formula (IPF), a partially hydrolysed formula (PHF), and an extensively hydrolysed formula (EHF). Methods: This was a double-blind, randomized, cross-over study. Following a fasting period of � 3 h, 20 healthy newborns were fed IPF, PHF, and EHF containing 50 ml 13 C-octanoic acid (OA). Breathsamplesweretakenbeforefeedingandevery15 minfor4 hthereafter. 13 C-OAbreathtest was assessed by isotope-ratio mass spectrometry, and GE half-times (t1/2) were determined.