Microbiologic contamination of a positive- and a neutral- displacement needleless intravenous access device in clinical use.

The use of a positive-displacement needleless intravenous access device was associated with lower microbial contamination rates compared with a neutral-displacement device when used on central venous catheters in hemato-oncology patients. In addition, rates of central line–associated bloodstream infection did not differ when either device was used.