Factors that influence cognitive function in epilepsy patients at neurology clinic Mohammad Hoesin Hospital Palembang

Background Epilepsy is a clinical manifestation of brain disorder due to various etiologies that needs appopriate treatment. Lack of therapy leade to cognitive impairment. This research aims to evaluate cognitive function profile and analyze factors that influence cognitive function in epilepsy patient. Method This is a cross sectional study of epilepsy patient in Mohammad Hoesin Hospital Palembang between January–May 2018 that fullfilled inclusion and exclusion criterias assesed by MOCA-Ina and questionnaire. Data was analyzed with SPSS 20.0 Chi-square, ANOVA and correlation for bivariate and double linear regression for multivariate. Result Samples consists 39 subjects. The prevalence of cognitive impairment in epilepsy patients was 69.2%. Level of education >9 years was mostly recorded from the samples with MOCA-Ina score that shows cognitive impairment. In multivariate analysis with multiple linear regression tests of 8 variables (age, sex, education level, age of onset, type of epilepsy syndrome, type of drug, duration of seizure, and frequency of seizures), three variables (gender, level of education, duration of seizure) had significant relationship with cognitive function of epilepsy patients. There was also a positive correlation between gender (0,333), education level (0,542) on cognitive function and a negative correlation (−0,334) between the duration of seizure and cognitive function. Conclusion The prevalence of cognitive impairment was 69.2% in epilepsy patients at Mohammad Hoeasin hospital Palembang. Level of education, gender and duration of seizure influence cognitive function in epilepsy patient.