Evaluation of Toothpaste Containing Aqueous Saffron Extract on Gingival Indices in Patients with Marginal Generalized Plaque Induced Gingivitis

Background: Gingivitis is an inflammatory disease involving the gums. Saffron contains various forms of flavonoids, glycosides, and anthocyanin compounds that are proven to have anti-inflammatory and antioxidant effects. This study evaluates the anti-inflammatory effects of Saffron stigma on gingival indices in patients with marginal generalized plaque-induced gingivitis.