Acalculous Cholecystitis as a Complication of Epstein-Barr Virus: A Case Report

Acute acalculous cholecystitis (AAC) is an uncommon disease mostly occurring in critically ill and immunosuppressed patients. Very few cases have been reported during the course of infectious diseases in particular Espstein-Barr virus (EBV). A wide range of complications have been reported in EBV infection including liver involvement that is usually self-limiting and characterized by mild elevation of liver enzymes. AAC during EBV infection can be the result of direct invasion of the virus or induced by cholestasis associated with infective hepatitis. Serological tests and ultrasound scan are the most common tools for diagnosis. Most cases resolve with antibiotic treatment. Very rarely a cholecystectomy is indicated. The authors present another case of the unusual association in a young female patient and review the literature.