Impact of the assist ventilation mode on work of breathing (WOB): neurally adjusted ventilatory assist (NAVA) versus pressure support ventilation (PSV) versus proportional assist ventilation plus (PAV+)

During assisted mechanical ventilation, appropriate WOB prevents diaphragm atrophy and fastens weaning. During PSV the ventilator support is fixed, irrespective of the patient's effort. On the contrary, both the NAVA and PAV + algorithms are designed to amplify patient's spontaneous effort. [1], [2]