[Correlation of hemoglobin concentration with the diameter of abdominal aortic aneurysm and long-term patient survival].

Objective To assessed the relationships between hemoglobin concentration from the patients with abdominal aortic aneurysm (AAA) and its diameter as well as patients' long-term survival.Methods Between January 2002 to June 2012, 255 AAA patients were reviewed retrospectively.The outcomes were compared between 3 groups of different treatments ( excluding 20 cases dead within 30 days).The procedures included open AAA repair ( n =76),endovascular (EVAR) ( n =62) and non-operated (n =97).The mean follow-up period was 63 ±42 months.The association of hemoglobin level with AAA diameter was assessed with multiple linear regression.Kaplan-Meier survival curves of anemic and non-anemic patient groups were compared by the log-rank method in 3 groups.Cox's proportional hazard regression mode was used to determine the effects of anemia on vital status after EVAR,open AAA repair or non-operation.Results A total of 88 (34.5％ ) of AAA patients had anemia.After adjustment for various risk factors,hemoglobin level was inversely correlated with maximal AAA diameter (β =-0.152,P =0.017).During a long-term follow-up,the 5-year survival rates were 56％,51％ and 42％ in anemic patients versus 94％,90％ and 80％ in non-anemic ones.Survival was lower in anemic patients than those without anemia in 3 groups ( P =0.005,0.001,0.025 by log-rank respectively).In three groups,according to multivariable Cox regression analysis,the hemoglobin levels were independently correlated with long-term mortality respectively after adjusting for various risk factors.The hemoglobin levels were correlated with death ( HR:0.923,0.963,0.963 ; P:0.001,0.002,0.028 ; 95％ CI:0.8798-0.970,0.941-0.986,0.932-0.996 ).Conclusion Hemoglobin concentration is independently associated with AAA diameter and reduced long-term survival after undergoing EVAR,open AAA repair and non-operation. Key words: Aortic aneurysm, abdominal;  Anemia;  Prognosis;  Retrospective studies