P378 BENEFICIAL EFFECT OF THE PROBIOTIC VSL-3 ON LIVER INJURY-ASSOCIATED SICKNESS BEHAVIOR DEVELOPMENT BY ALTERING SYSTEMIC IMMUNITY AND INHIBITING ACTIVATED MONOCYTES FROM ENTERING THE BRAIN

P378 BENEFICIAL EFFECT OF THE PROBIOTIC VSL-3 ON LIVER INJURY-ASSOCIATED SICKNESS BEHAVIOR DEVELOPMENT BY ALTERING SYSTEMIC IMMUNITY AND INHIBITING ACTIVATED MONOCYTES FROM ENTERING THE BRAIN C. D’Mello, M. Surette, W. Macnaughton, T. Le, C. di Simone, M.G. Swain. Liver Unit, University of Calgary, Calgary, AB, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada; Department of Experimental Medicine, University of L’Aquila, L’Aquila, Italy; Diviison of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, AB, Canada E-mail: swain@ucalgary.ca