Effectiveness of antithrombotic prophylaxis in paediatric cardiosurgical patients

Aim. To evaluate the effectiveness of prevention measures for thrombotic catheter-associated events in the perioperative management of patients undergoing cardiac surgery. Methods. A total of 433 paediatric and neonatal patients were included in the study during the period from January to December 2018. All patients received antithrombotic prophylaxis via systemic heparin administration. Results. Thirty-six patients displayed signs of thrombosis during the postoperative period (8.31%): 28 patients had venous thrombosis, while 6 had the Blalock-Taussig shunt thrombosis, and 2 had arterial thrombosis. The mortality rate was higher in the group with registered thrombosis than in the group without thrombosis (p = 0.01). Conclusion. The dosage regimen for children and neonatal patients should be according to age-associated antithrombotic drug standards. It requires an integral approach for evaluating the effectiveness of preventive and therapeutic measures. Received 25 August 2020. Revised 18 December 2020. Accepted 22 December 2020. Funding: The study did not have sponsorship. Conflict of interest: Author declares no conflict of interest.