Newly Designed Amperometric Biosensor for Hydrogen Peroxide and Glucose Based on Vanadium Sulfide Nanoparticles

In the present work, we describe a facile, green, and template-free solvothermal fabrication of vanadium sulfide (VS2) nanoparticles (NPs) and their application for the electrochemical detection of hydrogen peroxide (H2O2) and glucose. The morphology and composition of as-prepared samples were well-characterized by powder X-ray diffraction, energy-dispersive spectroscopy, transmission electron microscopy, scanning electron microscopy, UV–vis spectroscopy, and Brunauer–Emmett–Teller surface area measurement. Because of their interesting electrochemical responses toward H2O2, a novel nonenzymatic electrochemical sensor for H2O2 and glucose detection has been proposed based on a VS2 NP-modified glassy carbon electrode. The modified electrode showed an excellent electrochemical performance for the selective and sensitive nonenzymatic detection of H2O2 in a broad concentration range of 0.5 μM to 3.0 mM, with a wide linear range of 0.5 μM to 2.5 mM and a lower detection limit of 0.224 μM. The newly developed se...