Regional mechanics and energetics of stunned myocardium in vivo
2001
textabstractThere is still some controversy about the definition of ischemia. a tenn originally
derived from ischo hairna (to restrain blood). In this thesis. I would like to follow the
defInition of Robert Kloner: "Myocardial ischemia is that state in which blood flow
(oxygen and substrate delivery) to the myocardium has been reduced to the point where
myocardial metabolism shifts from aerobic to anaerobic and the products of anoxic
metabolism accumulate in the tissue. The reduction in blood flow may be absolute, as
occurs with a total coronary artery occlusion or relative, as occurs when there is an
increase in oxygen demand that outweighs oxygen supply (as in the case of a coronary
stenosis in the setting of exercise or rapid pacing)". The reason to choose this
definition lies in the fact that an absolute reduction in blood flow is not necessary for
ischemia. and that it clearly defInes when blood flow is inadequate. Apart from
myocardial stunning, which is defined below. several other ischemic syndromes have
been described. In this section I will concisely discuss ischemic preconditioning,
myocardial hibernation, and silent ischemia.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI