Type 2 diabetes is associated with decreased PGC1α expression in epicardial adipose tissue of patients with coronary artery disease

Inmaculada Moreno-Santos,Luis M. Pérez-Belmonte,Manuel Macías-González,María José Mataró,Daniel Castellano,Miguel A. López-Garrido,Carlos Porras-Martín,Pedro L. Sánchez-Fernández,Juan José Gómez-Doblas,Fernando Cardona,Eduardo de Teresa-Galván,Manuel F. Jiménez-Navarro

Type 2 diabetes is associated with decreased PGC1α expression in epicardial adipose tissue of patients with coronary artery disease

2016

Inmaculada Moreno-Santos
Luis M. Pérez-Belmonte
Manuel Macías-González
María José Mataró
Daniel Castellano
Miguel A. López-Garrido
Carlos Porras-Martín
Pedro L. Sánchez-Fernández
Juan José Gómez-Doblas
Fernando Cardona
Eduardo de Teresa-Galván
Manuel F. Jiménez-Navarro

Background Although recent studies indicate that epicardial adipose tissue expresses brown fat-like genes, such as PGC1α, UCP1 and PRDM16, the association of these genes with type 2 diabetes mellitus (DM2) in coronary artery disease (CAD) remains unknown.

Keywords:

Diabetes mellitus
Type 2 diabetes
Coronary artery disease
Epicardial adipose tissue
Type 2 Diabetes Mellitus
PRDM16
Medicine
Internal medicine
Cardiology
Coronary arteries
Ejection fraction
Adipose tissue
Thermogenin
Thermogenesis

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