Abstract 16682: Computational analysis of Right Ventricular Curvature From 3D echocardiography: Implications on Pulmonary Hypertension Severity

Introduction: Clinical significance of progressive right ventricular (RV) deformation in the evolution of left and right ventricular dysfunction is quite underinvestigated. Hypothesis: To investigate the role of geometrical RV changes in patients with pulmonary hypertension (PH) compared to normal, highlighting the dependence between morphology and the degree of pressure overload. Methods: RV reconstructions by 3D echocardiography were obtained in 20 subjects (10 controls, 10 PH). The 3D model of the RV was analyzed through a developed custom software that allows the computation of the curvature over the surface of the 3D model (figure a). Values of curvature were averaged over selected points. Results: In normal subjects the septum curvature assessed at end-diastole (ED) and end-systole (ES) was more concave (negative value: -0.30 ± 0.09 at ED and-0.27± 0.08 at ES) than in PH (positive value: 0.10 ± 0.25 at ED, 0.08 ± 0.23 at ES). A highest pressure overload induced a bulging of the septum into the left ...