The Routine Use of Quinidine in Acute Myocardial Infarction

DURING the course of a study on the use of Dicumarol in acute myocardial infarction, the value of the routine use of quinidine in this condition was also investigated. In particular, the investigation was directed toward ascertaining whether or not the incidence of arrhythmias and sudden unexpected death could be altered. The first 55 patients in the Dicumarol study had received no quinidine and were therefore designated as a control group. The remaining 66 patients received 0.2 gm. of quinidine sulfate by mouth four times a day, at 8 a.m., 12 noon, 4 p.m. and 8 p.m. This dosage schedule . . .