Intracranial haemorrhage in a neonate with severe haemophilia A: A case report and literature review
2012
Background:
Intracranial haemorrhage (ICH)
is a serious complication of haemophilia that affects
3.5–4 % of all boys with haemophilia during
the neonatal period. It is a leading cause of
mortality and morbidity in neonates with haemophilia.
Patients and Methods: The authors are presenting
a case of a neonate with severe haemophilia
A, who suffered postnatal ICH. They discuss dilemmas
regarding the optimal mode and management
of delivery in haemophilia carriers,
the role of imaging techniques in diagnosing
ICH and postpartum prophylaxis. Authors also
discuss the choice of factor concentrate for the
treatment of ICH and present the data on perinatal
complications in neonates with severe haemophilia
A in Slovenia in the period 1980–2010.
Conclusions:
ICH is a leading cause of mortality
and morbidity in neonates with coagulation
disorders. Early recognition of ICH and early appropriate
management are extremely important.
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