Does pyuria indicate infection in asymptomatic dialysis patients

It has been suggested that the finding of leukocyturia >10 WBC/HPF in asymptomatic dialysis patients predicts a positive urine culture and hence indicates urinary tract infection. Seventeen asymptomatic ESRD patients contributed clean catch specimens. Nine patients had ten or more WBC/HPF. One of these grew a possible pathogen in pure culture (23% of specimens excluding those growing multiple organisms). Thus, leukocyturia is not a good marker for positive urine culture and moreover is not demonstrated to indicate infection even when positive cultures follow.